In Europe, yes. But that was more of a "look this city has the plage. We'll wall it up until that's done with" kind of thing, and there was none of that mindset in the Americas. And even in Europe they didn't actually understand what was going on, and had no concept of incubation periods, or anything like that. The problem was that because of the extreme succeptibility of the native populations, they would literally have had to keep from having any physical contact with the Europeans at all. I mean, think of the stuff they keep saying about trying to contain potential bird flu, or mad cow disease. All it takes is to get the disease in, and it's too late.
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